Irisin deficiency disturbs bone metabolism

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Regulation of Bone Metabolism

Bone is formed through the processes of endochondral and intramembranous ossification. In endochondral ossification primary mesenchymal cells differentiate to chondrocytes and then are progressively substituted by bone, while in intramembranous ossification mesenchymal stem cells (MSCs) differentiate directly into osteoblasts to form bone. The steps of osteogenic proliferation, differentiation,...

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regulation of bone metabolism

bone is formed through the processes of endochondral and intramembranous ossification. in endochondral ossification primary mesenchymal cells differentiate to chondrocytes and then are progressively substituted by bone, while in intramembranous ossification mesenchymal stem cells (mscs) differentiate directly into osteoblasts to form bone. the steps of osteogenic proliferation, differentiation,...

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ژورنال

عنوان ژورنال: Journal of Cellular Physiology

سال: 2020

ISSN: 0021-9541,1097-4652

DOI: 10.1002/jcp.29894